ART-CHEM-BB B006886 - Names and Identifiers
ART-CHEM-BB B006886 - Physico-chemical Properties
Molecular Formula | C9H11N3
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Molar Mass | 161.2 |
Boling Point |
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Storage Condition | 2-8°C(protect from light) |
ART-CHEM-BB B006886 - Introduction
IMIDAZO [1,2-a] PYRIDIN-2-YLMETHYL-METHYL-AMINE is an organic compound with the formula C11H10N4, which has the following properties:
1. Appearance: IMIDAZO [1,2-a] PYRIDIN-2-YLMETHYL-METHYL-AMINE is a white crystalline solid.
2. Solubility: It is soluble in polar solvents such as water, ethanol and dimethyl sulfoxide.
3. Chemical properties: it is alkaline, can react with acid to generate salts. It can also participate in the nitration reaction, oxidation reaction and ring formation reaction of aromatic amines.
IMIDAZO [1,2-a] PYRIDIN-2-YLMETHYL-METHYL-AMINE is mainly used in organic synthesis, the specific uses are as follows:
1. Catalyst: It is often used as a catalyst for cross-coupling reactions, such as Suzuki coupling reactions.
2. Drug synthesis: It is an important intermediate for the synthesis of some drugs and physiologically active substances. For example, it can be used to synthesize the anti-blood cancer drug Imatinib.
3. Dye synthesis: It can be used to synthesize dyes, such as pyrazolopyrrole fixing agent.
IMIDAZO [1,2-a] PYRIDIN-2-YLMETHYL-METHYL-AMINE can be prepared by the following methods:
1. Application of metal catalyzed reaction synthesis: through metal catalyst, such as palladium catalysis, the aniline compound and β-keto acid compound under appropriate conditions, the target product is generated.
2. Synthesis of Nitrogen Heterocyclic Compounds: 1,2-dichloroethane and N-methylimidazole are reacted to generate 1,2-dichloro-5-methylimidazole, and then reacted with pyridine Dione to generate IMIDAZO[1,2-A]PYRIDIN-2-YLMETHYL-METHYL-AMINE.
When using and handling IMIDAZO [1,2-a] PYRIDIN-2-YLMETHYL-METHYL-AMINE, you need to pay attention to the following safety information:
1. Avoid contact with skin and eyes: protective gloves, protective glasses and protective mask is necessary.
2. Avoid inhalation and intake: During operation, protective masks and protective workbenches should be used to ensure good ventilation conditions.
3. Storage and transportation: the compound should be stored in a dry, ventilated and dark place, avoid contact with oxidants, acids, alkalis and other substances.
Please operate with caution and follow the correct laboratory operating procedures and safe operating instructions.
Last Update:2024-04-09 21:21:28